GROUP AS AN OBJECT: IMMATURITY OR DESTRUCTION?

[Immaturity of brain as an endophenotype of neuropsychiatric disorders].

Schizophrenia and bipolar disorder are severe neuropsychiatric disorders, affecting about 1% of the population. Identifying endophenotypes in the brains of neuropsychiatric patients is now considered the way to understand the underlying mechanisms and to improve therapeutic outcomes. However, the endophenotypes and brain mechanisms of the disorders remain unknown. We have previously reported th...

Divisible Designs Admitting, as an Automorphism Group, an Orthogonal Group Or a Unitary Group

MS as a disease of immaturity

The real role of reelin ttractants and repellents shunt neurons into their correct final location. But now Iris Hack, Harold Cremer (Université Mediterranée, Marseille, France), and colleagues have found evidence that reelin fits into neither of these categories. They propose, instead, that reelin converts cells that are migrating in association with each other into individual cells that can st...

File-Sharing: Creative Destruction or just Plain Destruction?

The ‘sharing’ of sound recordings over the Internet is the newest controversy in a long running battle between copyright owners and copying technologies. In order to provide some context, perspective and background, this paper examines the short history of file-sharing, the longer history of record sales, various explanations for the change in record sales and some analysis of the economics of ...

Competing DNS Roots: Creative Destruction or Just Plain Destruction?

The Internet Domain Name System (DNS) is a hierarchical name space that enables the assignment of unique, mnemonic identifiers to Internet hosts and the consistent mapping of these names to IP addresses. The root of the domain name system is the top of the hierarchy and is currently managed by a quasi-private centralized regulatory authority, the Internet Corporation for Assigned Names and Numb...